PSU Mark
Eberly College of Science Mathematics Department

Meeting Details

For more information about this meeting, contact Minxin Chen, Qingtian Zhang.

Title:Proton transport and its role in cancer research
Seminar:Mathematical Biology and Physiology Seminar
Speaker:Duan Chen, University of North Carolina at Charlotte
Abstract: Tumors have distinct properties from normal tissues, such as lower oxygen tension, stronger acidity and faster reducing rate. These biomarkers exist in a wide range of solid tumors and the corresponding microenvironment is critical for tumor development and design of anti-cancer treatments. Multiscale mathematical models are necessary to discover the macroscopic tumor growth at the tissue level and microscopic molecular interactions. Aiming at the tumor acidity, in this talk I will first introduce a quantum dynamic model for proton transport through membrane proteins and related numerical algorithms for simulation challenges. Then I will introduce a free boundary problem based tumor growth model for interactions among cancer cells and immune system at the tissue level. These two type of models and computational tools are fundamental building blocks for future multiscale model of tumor growth with complicated microenvironmental changes.

Room Reservation Information

Room Number:MB216
Date:10 / 17 / 2013
Time:11:00am - 01:00pm