Time: 4:00 p.m.
Location: 114 McAllister Building
Name: Steven J. Schiff
Affiliation: The Pennsylvania State University
Title: Spatiotemporal Organization and Control of Cortical Dynamics
Abstract: Although the identification of oscillatory dynamics following stimulation of the sensory sheets of m ammalian cortex has been long established, the spatiotemporal organization of such oscillations have not been well studied. We here describe the dynamical organization and evolution of oscillatory pattern formation in the middle cortical layers of rat visual cortex using voltage sensitive dyes. These episodes follow a pattern of spatiotemporal irregular and high dimensional activity, which spontaneously organize into spiral, plane, and ring waves, followed by gradual dissolution into irregular wave activity prior to episode termination. We demonstrate using a principal orthogonal decomposition that these dynamics evolve within a phase space whose dimensions shrink and expand consistently regardless of the specific wave type observed, and that this consistency is reflected in both amplitude as well as the frequency domain. Such dynamics can be modeled with fundamental differential equation models, as well as with empirical mode derived models. We will demonstrate how both strategies can be employed to observe and predict the state of such a system, and demonstrate a combined approach to model based control of such dynamics.
