PSU Mark
Eberly College of Science Mathematics Department

Meeting Details

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Title:Segmentation of Brain MR Image Sequences using the Level Set
Seminar:CCMA PDEs and Numerical Methods Seminar Series
Speaker:Corina S Drapaca, PSU
Abstract: The automated extraction of the cerebrospinal fluid-tissue boundary, particularly around the ventricular surface, from serial structural MRI of the brain acquired in imaging studies of aging and dementia is a challenging segmentation problem because of the common occurrence of peri-ventricular lesions which locally alter the appearance of white matter. We examine a level set approach which evolves a 4D description of the ventricular surface over time. This has the advantage of allowing constraints on the contour in the temporal direction, improving the consistency of the extracted object over time. A short review of the level set methods used in image segmentation is given. We then follow the approach proposed by Chan and Vese which is based on the Mumford and Shah model and implemented using the Osher and Sethian level set method. We have extended this to the 4D case to propagate a 4D contour toward the tissue boundaries through the evolution of a 5D implicit function. This model is then adapted to allow intensity contrast changes between time frames in the MRI sequence. Results on time sequences of 3D brain MR images are presented and discussed.

Room Reservation Information

Room Number:MB216
Date:10 / 22 / 2007
Time:03:35pm - 04:25pm